Select Research Presentations

From CRS annual meeting 2004

Supporting Publications

Selected articles from PMPS, Pharmaceutical Manufacturing and Packing Sourcer:

Selected articles from Drug Delivery Technology:

Bibliography

CHAPTERS IN BOOKS

1. A. R. FASSIHI and M. S. PARKER: Chapter 6: Controlled Drug Delivery, In Pharmaceutical Technology: Controlled drug release. Vol. 1, Ed. M. H. Rubinstein, Ellis Horwood Ltd., John Wiley & Sons, UK(1987) pp 64-71.
2. A. R. FASSIHI and I KANFER: Chapter 16: The effect of compressibility and powder flow properties on tablet weight variation; in Pharmaceutical Technology, Tableting Technology, M. H. Rubinstein, John Wiley & Sons, UK (1987) pp 189-202.
3. A. R. FASSIHI.
   Preservation of medicines against microbial contamination, in: Chapter 50: 4th. Edition ; Disinfection, Sterilization and Preservation; Ed. S. S. Block, Lea & Febiger, Philadelphia, USA. (1991) pp 871-886.
4. REZA FASSIHI
   Preservation and Microbiological Attributes of Non-Sterile Pharmaceutical Products, Chapter 64: In 5th Edition of Disinfection, Sterilization and Preservation; Ed. Seymour S. Block, Ph.D. Lippincott Williams and Wilkins 2000, pp 1263-1281.

PEER REVIEWED FULL PUBLICATIONS IN JOURNALS; AND PAPERS PUBLISHED IN VARIOUS CONFERENCE PROCEEDINGS

1. A. R. FASSIHI, M. S. PARKER and N. POURKAVOOS.
   Controlled release delivery: effect of particle size, compression force and temperature. Proceedings of the 4th. Pharm. Tech. Conference, Edinburgh, Scotland, April (1984), 10-12.
2. A. R. FASSIHI.
   A new generation of polymers for controlled drug delivery. S.A.J. Sci., 81:586, (1985).
3. A. R. FASSIHI, M. S. PARKER and N. POURKAVOOS.
   Solid dispersion controlled release: Effect of particle size compression force and temperature. Drug Development and Industrial Pharmacy, Vol. II: Nos 2 and 3: 523-535 (1985).
4. A. R. FASSIHI.
   Compression characteristics of polymers in tablet formulations. 5th. Int. Pharm. Tech. Conference, Harrogate, England (1986), Vol II: 222- 227.
5. A. R. FASSIHI and M. S. PARKER
   Release kinetics from heterogenous polymeric matrices. 5th. Int. Pharm. Tech. Conference, Harrogate, England (1986), pp 97-111.
6. A. R. FASSIHI and I. KANFER.
   Effect of compressibility and powder flow properties on tablet weight variation. Drug Development and Ind. Pharm. 12 (11-13), 1947, (1986).
7. A. R. FASSIHI and I. KANFER.
   Compressibility and powder flow properties. 5th. Int. Pharm. Tech. Conference, Harrogate, England, 255-275 (1986).
8. A. R. FASSIHI.
   Mechanisms of disintegration and compactibility in a direct compression system. International Journal of Pharmaceutics, 32 (1986), 93-96.
9. A. R. FASSIHI.
   Continuous matrix formation for controlled drug release: compression of isotropic polymeric system. International Journal of Pharmaceutics, 34 (1986) 169-172.
10. A. R. FASSIHI and M. S. PARKER.
    Controlled drug release from a compressed heterogeneous polymeric matrix: kinetics of release. Drug Develop and Ind. Pharm. 12 (11-13), 1649- 1661 (1986).
11. A. R. FASSIHI.
    Kinetics of drug release from solid matrices. International Journal of Pharmaceutics, 37 (1987) 119-125.
12. A. R. FASSIHI and M. S. PARKER.
    Gamma irradiation of gelatin: effects on the rigidity index and the granulation process. Seventh International Biodeterioration symposium Cambridge, UK Sept. (1987), Elsevier Science Publishers BV.
13. A. R. FASSIHI.
    Hydrogel: A novel disintegrant in tablet formulation. J. Pharm. Pharmacol. (1987) 129S.
14. A. R. FASSIHI.
    Consolidation behavior of polymeric substances in non-disintegrating solid matrices. International Journal of Pharmaceutic (1988) 44, 249-256.
15. A. R. FASSIHI.
    Interrelationships between yield pressure, moisture content and tensile strength of microcrystalline cellulose compacts. J. Pharm. Pharmacol. (1988) 76P.
16. A. R. FASSIHI.
    in vitro and in vivo evaluation of controlled release preparation of theophylline. J. Pharm. Pharmacol. (1988), 32P.
17. A. R. FASSIHI, R. DOWSE and S. D. ROBERTSON.
    Effects of dietary cellulose on the absorption and bioavailability of theophylline. Int. J. Pharmaceutics (1989), 41: 369-372.
18. A. R. FASSIHI and D. L. MUNDAY.
    Dissolution of theophylline from film coated slow release mini-tablets in various dissolution media. J. Pharm. Pharmacol. (1989), 41: 369-372.
19. D. L. MUNDAY and A. R. FASSIHI.
    Controlled release delivery: Effect of coating composition on release characteristics of mini-tablets. Int. J. Pharmaceutics, (1989), 52, 109-114.
20. D. L. MUNDAY and A. R. FASSIHI.
    Changes in drug release rate; effect of temperature asnd relative humidity on polymeric film coatings, 5th. Int. Pharm. Confr. Paris, June (1989), Vol. II. 55-60.
21. A. R. FASSIHI.
    Characteristics of hydrogel in solid dosage technology. J. Pharm. Pharmacol. (1989), 41: 853-855.
22. REZA FASSIHI
    Biopharmaceutical aspects of drug formulations S.A.Pharm.J. (1990), 5:151-156.
23. REZA FASSIHI
    Biopharmaceutical aspects of intestinal drug absorption S.A.Pharm.J. (1990), 7:259-265.
24. D. L. MUNDAY, A. R. FASSIHI and C. DeVILLIERS.
    Bioavailability study of a theophylline oral controlled release capsule containing film coated mini-tablets in beagle dogs. International J. Pharmaceutics, Vol. 69: 123-127 (1991).
25. A. R. FASSIHI, ROSE DOWSE, SIRION S. D. ROBERTSON.
    Influence of sorbitol solution on the bioavailability of theophylline. Int. J. Pharm. 72 (1991) 175-178.
26. D. L. MUNDAY, A. R. FASSIHI and C. DeVILLIERS.
    Multiple dose in vivo evaluation of an oral controlled release capsule dosage form of theophylline containing film coated mini-tablets in beagle dogs. Int. J. Pharm. 73 (1991) 89-93.
27. M. DANCKWERTS and A. R. FASSIHI.
    Implantable controlled release drug delivery systems. Drug Develop and Ind. Pharm. 17 (11), 1465-1502 (1991).
28. D. L. MUNDAY and A. R. FASSIHI.
    Changes in drug release rate: effect of stress storage conditions on polymeric film coated mini-tablets. Drug Develop. Ind. Pharm. 17 (15), 2135-2143 (1991).
29. T. DURIG and A. R. FASSIHI.
    Preformulation study of moisture effect on the physical stability of pyridoxal hydrochloride. Int. J. Pharm., 77, 315-319 (1991).
30. W. A. RITSCHEL, N. N. VACHHARAJANI, H. FORUSZ and A. R. FASSIHI.
    On the Mechanism of effect of fatty acids on gastric emptying. Proceedings of the I Reunion cientifica de'la Association de Docentes de'Farmacia Galenica: Madrid, Spain p. p. 27-28 (1992).
31. A. R. FASSIHI and E. A. RITSCHEL
    Multiple-layer, direct compression, controlled release system: in vitro and in vivo evaluation. J. Pharm. Sci. Vol. 82, No. 7, 750-754 (1993).
32. D. L. MUNDAY and A. R. FASSIHI
    Changes in drug release rate 2: effect of temperature and relative humidity on polymeric film coatings. 5th International Conference on Pharmaceutical Technology Paris May 30th - June 1, 1989, 55-60.
33. T. DURIG and A. R. FASSIHI
    Identification of stabilizing and destabilizing effects of excipient-drug interactions in solid dosage form design. Int. J. Pharm. 97, 161-170, (1993).
34. W. A. RITSCHEL, N. N. VACHHARARAJANI, and A. R. FASSIHI.
    In-vitro model optimization of antacid evaluation based on physiological constraints and human gastric pH. Pharm. Pharmacol. Lett. 2:58-61 (1992).
35. R. FASSIHI
    Microporous mini-tablets for controlled delivery and fine dose titration. Proceed. 20th. Intern. Symp. Control. Rel. Bioact. Mater., Washington, D.C. pp. 388-389 (1993).
36. R. FASSIHI
    Fluctuating release rate delivery system for drugs influenced by chronobiologic functions. Proceed. 20th. Intern. Symp. Control. Rel. Bioact. Mater., Washington, D.C. pp. 38-39 (1993).
37. R. FASSIHI, A.M. McPHILLIPS, S.A. URAIZEE and A.M. SAKR
    Potential Use of Magnesium Stearate and Talc as Dissolution Retardants in the Development of Controlled Drug Delivery Systems. Pharm. Ind., 56, 6, 579-583 (1994).
38. D. L. MUNDAY and A. R. FASSIHI
    In-vitro - in-vivo correlation studies on a novel controlled release theophylline delivery system and on Theo-Dur tablets. Int. J. Pharm., 118-251-255 (1995).
39. L. YANG and R. FASSIHI
    Zero-order release kinetics from self-correcting floatable asymmetric configuration drug delivery system. J. Pharm. Sci. 85, 170-173 (1996).
40. R. FASSIHI, J. FABIAN and A M. SAKR.
    Application of Response Surface Methodology to design optimization in formulation of a typical controlled release system. Pharm. Industry,57, 12, 1039-1043 (1995).
41. L. YANG, G. VENKATESH, AND R. FASSIHI
    Characterization of Compressibility and Compactibility of Poly(ethylene oxide) Polymers for Modified Release Application by Compaction Simulator. J. Pharm. Sci. 85, 1085-1090 (1996).
42. L. YANG and R. FASSIHI
    Modulation of diclofenac release from a totally soluble controlled release drug delivery system. Journal of Controlled Release 44, 135-140 (1997)
43. REZA FASSIHI, AMIR RAZAGHI, HYUNJO KIM, LIBO YANG, JUNE FABIAN
    Pitfalls in Release Studies of Floatable or Sticking Delivery Systems Proceedings of Controlled Release Society, Baltimore, August, 121-122 (1996).
44. LIBO YANG AND REZA FASSIHI
    Diclofenac Delivery System Design Based on Biopharmaceutical Considerations Proceedings of Controlled Release Society, Baltimore, August, 123-124 (1996).
45. HYUNJO KIM AND REZA FASSIHI
    Optimal Delivery System for Colonic Drug Targeting Proceedings of Controlled Release Society, Baltimore, August, 125-126 (1996).
46. AMIR M. RAZAGHI AND REZA FASSIHI
    Evaluation of Diffusion Controlled Release From Topical Steroid Products Proceedings of Controlled Release Society, Baltimore, August, 127- 128 (1996).
47. R. FASSIHI, J. FABIAN AND A.M. SAKR
    Application of Response Surface Methodology to Design Optimization in Formulation of a Typical Controlled Release System. Drugs made in Germany 39, 122-126 (1996).
48. HYUNJO KIM AND REZA FASSIHI
    Ternary Polymeric Matrix System a New Approach in Controlled Release. Drug Delivery of Highly Soluble Drugs: I-Diltiazem Hydrochloride. Pharm. Res. Vol. 14, No. 10, 1415-1421 (1997).
49. HYUNJO KIM AND REZA FASSIHI
    Application of Binary Polymer System in Drug Release Rate Modulation: I -Characterization of Release Mechanism J. Pharm. Sci, 86, 316-322 (1997).
50. HYUNJO KIM AND REZA FASSIHI
    Application of Binary Polymer System in Drug Release Rate Modulation: II - Influence of Formulation Variables and Hydrodynamic Conditions on Release Kinetics. J. Pharm. Sci, 86, 323-328 (1997).
51. HYUNJO KIM, GOPI VENKATESH AND REZA FASSIHI
    Compactiblity Characterization of Granular Pectin for tableting operation using a compaction simulator Int. J. Pharm. 161, 149-159 (1998)
52. LIBO YANG AND REZA FASSIHI
    Examination of Drug, Polymer, Hydrodynamics and Compositional Effects on Release Rate from a triple-layer Asymmetric Configuration Delivery System Int. J. Pharm. 155 , 219-229 (1997).
53. LIBO YANG, GOPI VENKATESH AND REZA FASSIHI
    Compaction Simulator Study of a Novel Triple-Layer Matrix for industrial Tableting. Int. J. Pharm. 152 , 45-52 (1997).
54. THOMAS DURIG AND REZA FASSIHI
    Mechanistic Evaluation of Binary Effects of Magnesium Stearate and Talc as Dissolution Retardants at 85% Drug Loading in an Experimental Extended Release Formulation. J. Pharm. Sci., 86, No. 10, 1092-1098 (1997).
55. LIBO YANG AND REZA FASSIHI
    Verapamil Delivery System based on biopharmaceutical considerations. 24th International Symposium on Controlled Release of Bioactive Materials, Stockholm, June 15-19, (1997).
56. V. PILLAY AND R. FASSIHI
    Evaluation and comparison of dissolution data dervied from different modified release dosage forms: An alternative method. J. Controlled Rel., 55, 45-55 (1998).
57. L. YANG, B. JOHNSON AND R. FASSIHI
    Determination of continuous changes in thegel layer thickness of poly(ethylene oxide) and HPMC tablets undergoing hydration: Application of Texture Analyzer. Pharm. Res. 15, 1902-1906 (1998).
58. L. YANG , J. ESHRAGHI, AND R. FASSIHI
    A new system for controlled and concomitant intragastric delivery of tetracycline, metronidazole and bismuth salts for the treatment of Helicobater pylori associated gastric ulcer J. Controlled Rel. 57, 215-222 (1999).
59. V. PILLAY AND R. FASSIHI
    In-vitro release modulation for site-specific drug delivery to the gastrointestinal tract I : Comparison of pH-responsive drug release and associated kinetics. J. Controlled Rel. 59, 229-242 (1999).
60. V. PILLAY AND REZA FASSIHI
    In-vitro release modulation for site -specific drug delivery to the gastrointestinal tract II : Physicochemical characterization of calcium-alginate,calcium-pectinate and alginate-pectinate pellets. J. Controlled Rel. 59, 243-256 (1999).
61. V. PILLAY AND REZA FASSIHI
    A new method for dissolution studies of lipid-filled capsules employing nifedipine as a model drug. Pharm. Res. 16, 333-337 (1999).
62. V. PILLAY AND REZA FASSIHI
    Unconventional dissolution methodologies. J. Pharm. Sci., vol. 88, 9, 843-851 (1999).
63. T. DURIG AND REZA FASSIHI
    Functionality of a high drug load particulate system designed for an erodible extended release matrix tablet II: Effect of compaction variables and lubricant levels on drug release. J. Pharm.and Pharmacol. (in press).
64. T. DURIG, G.M. VENKATESH AND REZA FASSIHI
    An investigation into the erosion behaviour of a high drug- load (85%) particulate system designed for an extended-release matrix tablet. Analysis of erosion kinetics in conjunction with variations in lubrication, porosity and compactionrate. J. Pharm. Pharmacol., 55: 1085-1092 (1999).
65. V. PILLAY AND REZA FASSIHI
    Electrolyte- induced compositional heterogeneity in tablet matrix for rate-controlled drug delivery. J.Pharm.Sci., Vol.88, No.11, 1140-1148 (1999).
66. V. PILLAY AND REZA FASSIHI
    In-situ electrolyte interactions in a disk compressed configuration system for up-curving and constant release kinetics. J. Controlled Release, 67, 55-65, (2000).
67. V. PILLAY AND REZA FASSIHI
    Zero order delivery of a 100% water soluble drug from a directly compressed monolithic system: Metoprolol tartarate. J. Controlled Release, 67, 67-78 (2000).
68. THOMAS DURIG AND REZA FASSIHI
    Evaluation of Floating and Sticking Extended Release delivery Systems: An Unconventional Dissolution Test. J.Controlled Release, 67, 37-44, (2000).
69. V. PILLAY AND REZA FASSIHI
    Probing the dynamics of matrix hydration in the presence of electrolytes. Drug Delivery, 8; 87-92, (2001).
70. S. ZULEGER, R. FASSIHI AND B. C. LIPPOLD
    Texture Analysis and Photomicroscopy to Investigate the Swelling of Controlled Release Cellulose Ether Tablets. European J.Pharm. Sci.; Accepted for publication 2002.
71. T.DURIG AND REZA FASSIHI
    Gar-based monolithic matrix systems: Effect of ionizable and non-ionizable substances and excipients on gel dynamics and release kinetics. Journal of Controlled Release, Vol. 80 (1-3) pp 45-56, 2002.
72. V. PILLAY, M.P. DANKWERTS AND REZA FASSIHI
    A crosslinked calcium-alginate-pectinate-cellulose acetophthalate gelisphere system for linear drug release. Drug Delivery, 9:77-86, (2002).
73. S. ZULEGER, R. FASSIHI AND B. LIPPOLD
    Polymer particle erosion controlling drug release. II. Swelling investigations to clarify the release mechanism. International Journal of Pharmaceutics, 247, 23-37 (2002).
74. S. Turner, M. Hite, C. Federici and Reza Fassihi
    Development of a High Drug Load Monolithic Controlled Release Oral Delivery System for Niacin: A Novel Approach Drug Delivery Technology; Vol. 3; No. 2; March/April issue, 2003.
75. T. DURIG, G.M. VENKATESH AND REZA FASSIHI
    Compactibility of a high drug load (85%) agglomerated system designed for an extended release matrix tablet: Effect of variations in lubricant level, porosity and compaction rate. J. Pharm. Pharmacol. (submitted for publication).
76. R. Talukder and Reza Fassihi
    GASTRORETENTIVE DELIVERY SYSTEMS: HOLLOW BEADS. Drug Development and Industrial Pharmacy (submitted for publication).
77. R. Talukder, and R. Fassihi
    GASTRORETENTIVE DELIVERY SYSTEMS: A MINI REVIEW Drug Development and Industrial Pharmacy (submitted for publication).
78. S. Turner, C. Federici, M. Hite and R Fassihi
    Formulation development and human in vitro-in vivo correlation for a novel monolithic controlled release matrix system of high load and highly water soluble drug Niacin. Drug Development and Industrial Pharmacy, Vol. 30, No. 8, pp. 797-807, 2004.